منابع مشابه
Glomerular lesions in acute tubular necrosis.
Infraglomerular epithelial reflux has been described as an early microscopic lesion in the kidney of patients with acute renal failure. In our series of forty-four cases of acute tubular necrosis none showed this finding; however, in two cases lesions remotely similar to infraglomerular epithelial reflux and often known as 'glomerular masses' were present. No significance can be attached to the...
متن کاملAPOL1 Genotype and Glomerular and Tubular Kidney Injury in Women With HIV.
BACKGROUND APOL1 genotype is associated with advanced kidney disease in African Americans, but the pathogenic mechanisms are unclear. Here, associations of APOL1 genotype with urine biomarkers of glomerular and tubular injury and kidney function decline were evaluated. STUDY DESIGN Observational study. SETTING & PARTICIPANTS 431 human immunodeficiency virus (HIV)-infected African American w...
متن کاملThe significance of tubular and glomerular proteinuria in critically ill patients with severe acute kidney injury
OBJECTIVE Critically ill patients with acute kidney injury (AKI) frequently need acute renal replacement therapy (aRRT). We evaluated an inexpensive, rapid quantitative and qualitative analysis of proteinuria on the course of AKI patients requiring aRRT in intensive care. METHOD This was a prospective, observational study of critically ill patients with severe established AKI or Acute on Chro...
متن کاملTubular and Glomerular Injury in Diabetes and the Impact of ACE Inhibition
OBJECTIVE We studied tubular and glomerular damage in type 1 diabetic patients by measuring urinary-liver fatty acid binding protein (U-LFABP) and albuminuria. Subsequently, we evaluated the effect of ACE inhibition on U-LFABP in patients with diabetic nephropathy. RESEARCH DESIGN AND METHODS We studied Caucasians with type 1 diabetes: 58 with normoalbuminuria (urinary albumin <30 mg/24 h), 4...
متن کاملIntravital imaging of podocyte calcium in glomerular injury and disease.
Intracellular calcium ([Ca²⁺]i) signaling mediates physiological and pathological processes in multiple organs, including the renal podocyte; however, in vivo podocyte [Ca²⁺]i dynamics are not fully understood. Here we developed an imaging approach that uses multiphoton microscopy (MPM) to directly visualize podocyte [Ca²⁺]i dynamics within the intact kidneys of live mice expressing a fluoresce...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2003
ISSN: 0085-2538
DOI: 10.1046/j.1523-1755.2003.00795.x